Dr. Morgan’s Microbes Questions #2 – Antibacterial Agents

1. Antibiotic choice for pneumonia due to Legionella pneumophila:

a. Penicillin
b. Macrolide antibiotic/Erythromycin
c. Trimethoprim/Sulfamethoxazole
d. Imipenem
e. Vancomycin

2. Antibiotic choice for Enterococcus faecalis endocarditis:

a. Cefotaxime
b. Erythromycin plus Gentamicin
c. Tetracycline
d. Ampicillin plus Gentamicin
e. Trimethoprim/Sulfamethoxazole

3. Antibiotic choice for complicated pneumonia caused by Streptococcus pneumoniae with a Penicillin MIC = 4 mcg/ml and susceptible to other antibiotics tested.

a. Penicillin
b. Cefotaxime
c. Vancomycin
d. Imipenem
e. Ertapenem

4. Antibiotic choice for bacteremia caused by a Staphylococcus aureus strain detected to have a mecA gene:

a. Ampicillin
b. Vancomycin
c. Cefotaxime
d. Cefazolin
e. Imipenem

5. Antibiotic choice for a urinary tract infection caused by Klebsiella pneumoniae detected to have carbapenamase enzyme:

a. Ampicillin
b. Ceftriaxone
c. Gentamicin
d. Colistin
e. Imipenem

6. Antibiotic  choice to treat bacteremia caused by Escherichia coli with a CTX-M type enzyme:

a. Imipenem
b. Cefotaxime
c. Ampicillin
d. Cefazolin
e. Ceftriaxone

7. A Staphylococcus aureus isolate was determined to be “D” test positive – this eliminates the ability to use which antibiotic  to treat a patient with soft tissue infection:

a. Ampicillin
b. Vancomycin
c. Clindamycin
d. Erythromycin
e. Cefazolin

8. An immune suppressed cancer patient was diagnosed with Listeria monocytogenes bacteremia.  The best choice for therapy would be:

a. Cefazolin
b. Ampicillin
c. Gentamicin
d. Ceftriazone
e. Cefotazime

9. An elderly adult is diagnosed with Haemophilus influenza meningitis.  The H. influenza is found to produce a beta-lactamase enzyme by the cefinase test.   The positive reaction eliminates the ability to use which antibiotic:

a. Cefotaxime
b. Ceftriaxone
c. Ampicillin
d. Vancomyin
e. Erythromycin

10. A 35 year old male was diagnosed with diarrhea caused by Shigella flexneri and required antibiotic  therapy.  The best choice for therapy would be:

a. Tetracycline
b. Ciprofloxacin
c. Erythromycin
d. Vancomycin
e. Clindamycin

Keys to the questions:  1.b  2.d  3.b  4.b  5.d  6.a  7.c  8.b  9.c  10.b